SPRAVATO® (Esketamine) Nasal Treatment for Depression in Reno

If you are struggling with depression that hasn’t responded to traditional oral antidepressants, SPRAVATO® (esketamine) may offer a breakthrough. At Thunder Pain & Wellness, we provide this FDA-approved nasal therapy in a safe, medically supervised environment, offering hope and rapid relief for those who need it most.

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What is SPRAVATO® and How Does it Work?

SPRAVATO® (pronounced sprah-VAH-toe) is the first and only FDA-approved nasal spray containing esketamine—a derivative of ketamine that targets the brain's glutamate system. Unlike traditional antidepressants that can take weeks to work, SPRAVATO® acts on different neurotransmitter pathways involved in mood regulation, which may help improve symptoms more quickly for some patients.

Who is a Candidate for Esketamine Therapy?

SPRAVATO® is specifically indicated for adults who:


  • Have a diagnosis of Treatment-Resistant Depression (TRD).
  • Have tried at least two antidepressant medications without adequate improvement.
  • Have Major Depressive Disorder (MDD) with acute suicidal ideation or behavior.

Not everyone will qualify, and a clinical assessment at our Reno office is required to determine if this therapy is the right fit for you.

The Treatment Process: What to Expect

Because SPRAVATO® can cause temporary sedation or changes in blood pressure, it must be administered in a certified medical setting under direct supervision.

  • In-Office Administration: You will administer the nasal spray yourself under the guidance of our clinical team.
  • Safety Monitoring: You will rest in a comfortable, private room for approximately two hours while we monitor your response.
  • The Journey Home: You must have a friend or family member drive you home after each session. You cannot drive or operate machinery until the following day.
  • Schedule: Treatment typically begins with twice-weekly sessions for the first month, moving to a maintenance schedule based on your progress.

Is SPRAVATO® Covered by Insurance?

Yes. Because SPRAVATO® is FDA-approved, it is widely covered by Medicare and most major commercial insurance plans when medical criteria are met.

At Thunder Pain & Wellness, we understand that insurance paperwork can be overwhelming. Our team handles the prior-authorization process for you, verifying your benefits and providing a clear breakdown of any out-of-pocket costs before you begin treatment.

View Our Insurance & Pricing List

Safety & Potential Side Effects

SPRAVATO® is generally well-tolerated. During your two-hour observation period, our staff is present to manage any common side effects, which may include:

  • Dizziness or lightheadedness
  • Nausea or "feeling detached" (dissociation)
  • Temporary increase in blood pressure

Why Choose Thunder Pain & Wellness?

We aren't just a clinic; we are specialists in both interventional pain and mental health. We offer a calm, patient-focused environment where your safety and recovery are our only priorities.

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"They really listen to your needs and I can’t thank them enough…The Spravato program they have for Depression is amazing and has changed the way I think in a much more positive way. Thank you, Dr. Thunder!" — Rosamund T., Verified Google Review